The Scrubs revival is officially returning for another season, but viewers should expect some noticeable changes when the medical comedy comes back.
The original series, which aired from 2001 to 2010, followed the doctors, nurses and staff of the fictional Sacred Heart Hospital. Its best-known ensemble included Zach Braff, Sarah Chalke, Donald Faison, Judy Reyes, Neil Flynn, Ken Jenkins and John C. McGinley.
After the original storyline shifted significantly in its later years, Scrubs introduced a new medical-school setting and a younger group of characters. That version lasted only one season before the show came to an end.
Years later, the franchise returned with a revival, bringing several familiar faces back while introducing new characters.
Now that the revival has been renewed for season 2, some stars are staying, others are leaving and a few familiar characters are receiving expanded roles.
Here is where the cast currently stands based on the supplied report.
Zach Braff
Braff will remain one of the central stars of season 2.
His character, JD, has been at the heart of Scrubs since the original series and will once again be front and center when the revival returns.
Sarah Chalke
Chalke is also returning as Elliott.
Her continued involvement keeps another major piece of the original Scrubs ensemble in place for season 2.
Donald Faison
Faison will remain part of the main cast as well.
His longtime character has been one of the franchise’s most recognizable figures, making his return an important part of the revival’s connection to the original show.
Joel Kim Booster
Booster will not return for season 2.
He played Dr. Kevin Park during the first season of the revival, but his character will not be part of the next chapter.
Ava Bunn
Bunn is getting a bigger role.
After appearing previously, she has been promoted to series regular for season 2.
X Mayo
Mayo is another cast member who is not expected back.
She appeared in a recurring capacity as Charge Nurse Raymond during season 1.
Jacob Dudman
Dudman is expected to continue appearing in a recurring role during season 2.
David Gridley
Gridley will also return as part of the recurring cast.
His character remains connected to the group of interns introduced through the revival.
Layla Mohammadi
Mohammadi is expected to return in a recurring capacity as well.
Amanda Morrow
Morrow is also listed among the recurring season 2 cast members.
Rachel Bilson
Bilson’s role is set to become more significant.
After being introduced as Charlie, her involvement will expand when the revival returns for its second season.
John C. McGinley
McGinley will return in a recurring capacity.
His appearance brings another major original-series favorite back into the Scrubs universe.
Judy Reyes
Reyes is also expected to continue appearing in a recurring role while balancing other projects outside the series.
Her return helps maintain another important connection to the original Sacred Heart ensemble.
Scott Foley
Foley will reprise his role from the original Scrubs series in season 2.
His return adds another familiar face for longtime viewers and comes after he was previously unable to participate in the revival because of scheduling conflicts.
With several original stars remaining alongside new and expanded characters, season 2 appears to be balancing nostalgia with changes to the revival’s newer ensemble.
The departures of Joel Kim Booster and X Mayo will alter the season 1 lineup, while the expanded roles for Ava Bunn and Rachel Bilson suggest the series is continuing to reshape its supporting cast.
At the same time, Braff, Chalke, Faison, McGinley, Reyes and Foley ensure that longtime Scrubs fans will still have plenty of familiar faces when the show returns.
Season 2 therefore looks less like a complete reset and more like another evolution of the franchise — keeping its core history intact while adjusting the cast around it.
